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Writer's pictureVivek Roachthavilit

How The Endocannabinoid System Play A Role In Dermatological Disease

Lately, have you realized every time you read about CBD or cannabis in the news you will often come across the word, ”entourage effect". That's because while scientists were trying to understand how the likes of CBD and THC works with your body, they have found that there are chemical signals and receptors that run throughout your body and brain. Your body evidently creates its own cannabinoids which are therapeutic for your health and similar to what you may find from cannabinoids like THC, CBD, CBG, etc.  Incidentally, cannabinoids like CBD and THC interact with the endocannabinoid system to create a positive effect on your body and mind-hence the correlation between CBD and ECS.  There are cannabinoid receptors in your brain, mainly CB1 and CB2 receptors that pretty much act like a traffic control system that helps control and regulate some of the vital systems in your body for example your mood, appetite, pain sensation, sleep, alertness and body temperature.  We call this entire system the Endocannabinoid System (ECS). 


Researchers have also found that the ECS helps regulate your skin health too.  Anything from acne, eczema, rash and dermatological diseases.  In the past we have discussed how CBD may impact skin conditions, but today we will focus on how the endocannabinoid system plays a role in dermatological diseases as skin diseases do have a great significant impact on one's life.  It could lead to obstruction in self image, disturbance in everyday activities, lead to further health complications, bring on stress and anxiety which can result in depression too.  We will examine what the ECS can do for dermatological diseases.


Your Skin Is Filled With ECS!


The endocannabinoid is very much present in your skin and that's a big deal as your skin is the largest organ in your body.  With the ECS there are two main receptors and we call them CB1 and CB2.  CB1 and CB2 are mainly found in the sebocytes, keratinocytes, immune cells and sensory nerves in your skin.  Their main purpose is to regulate inflammation, apoptosis, proliferation and differentiation. 


Now that we know that the ECS is very much involved with the skin, let's go on and understand what roles it plays with dermatological diseases.  


ECS and Acne 


Acne is a result of an overactive response of the sebaceous gland and inflammation.  Scientists have found that cannabinoids especially CBD do show an ample amount of anti-inflammatory and sebostatic properties which can be beneficial to acne management. 


ECS With Psoriasis and Eczema


A hyperactive immune system and inflammation response are two leading causes to skin pathogenesis like eczema and psoriasis.  CBD and the ECS have shown potential in preclinical and clinical trials.  In various scientific studies it has shown that cannabinoids carry an abundance of anti-inflammatory, immunomodulatory, and antipruritic effects.  This is essential for treating and relieving patients from these skin conditions.


Cannabinoids and the ECS can offer much more than relieve your skin symptoms, but it can provide a much broader role in managing your skin health and prevent skin diseases.  It's important to take care of not just your body, mind, but skin too after all your skin covers your hold body.  There's many ways do to that like regular exercise, good diet, getting enough sleep, stay hydrated and using safe and high quality skin care for instance. But, you can also incorporate CBD products into your self-care routine to help boost your general health.  You can apply CBD topically onto your skin or ingest CBD oil orally.  Whether it's acne or eczema, whether is psoriasis or even sleep Mellow Organic have you covered.  Mellow 900 mg CBD Oil is made from CBD Isolate and available in Natural and Orange flavors.  Mellow 1,800 mg Full Spectrum CBD Oil for a higher CBD potency and Mellow CBD Soothing Balm vanilla scented with high quality CBD-infused topicals. 


Reported by Vivek Roachthavilit


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